In one small study (9 cases)28 the derived OR for the association between adiponectin and aggressive prostate cancer was implausibly small (0.02, 95% CI 0.00 to 0.13) and this estimate was excluded (but the effect estimate from this study for the association between adiponectin and overall prostate cancer was included). The gene discussed is ADIPOQ; the disease is prostate carcinoma.