Previous study has revealed that SNHG6 could repress the transcription of p21 via recruiting EZH2 to the promoter region of p21 in colorectal cancer cells14; to further understand the underlying mechanism for the function of SNHG6 in chondrosarcoma cells, we first performed immunoprecipitation assay with control IgG and anti-EZH2 antibody using SW1353 and HCS2/8 cell lysates, and the immunoprecipitate was then subjected to qRT-PCR. This evidence concerns the gene SNHG6 and chondrosarcoma.