The MTT assay proved that SNHG6 knockdown significantly impaired the viability of SW1353 and HCS2/8 cells, especially at 72 and 96 h after the assay initiation (Fig. 2B, C); meanwhile, both SW1353 and HCS2/8 cells transfected with shSNHG6-3 showed much less colonies then the control cells (Fig. 2D, E), which further suggested that SNHG6 was required for the proliferation of chondrosarcoma cells. Here, SNHG6 is linked to chondrosarcoma.