Notably, eight of the nine UVR-exposed mucosal melanomas and all 51 UVR-exposed cutaneous melanomas carried mutations in  one to eleven known melanoma genes, with the remaining mucosal melanoma (MuM10) carrying a frame-shift mutation in the melanocyte gene TYRP1 (Fig. 2c and Supplementary Data 1). This evidence concerns the gene TYRP1 and mucosal melanoma.