In NPC, correlation analysis showed that CD276 mRNA level was positively associated with the infiltration level of CD8-naive cell, nTreg cell, and Th2 cell (Fig. 5c), but was negatively associated with the infiltration level of CD4 T cell, Tfh cell, and Th1 cell (Fig. 5d). Here, CD8A is linked to nasopharyngeal carcinoma.