TARDBP and amyotrophic lateral sclerosis: Indeed, several reports of C9FTD/ALS cases showed affected individuals with DPR pathology but mild or absent TDP-43 pathology (Baborie et al., 2015; Gijselinck et al., 2012; Mori et al., 2013; Proudfoot et al., 2014; Vatsavayai et al., 2016).