Studies carried out in Drosophila demonstrates that nicotine improved survival of paraquat-treated flies, used as a Parkinson’s disease model, and modifies the expression patterns of particular genes as CG14691, one homologous gene of the human SV2C which encode a synaptic vesicle protein involved in the release of dopamine (Hill-Burns et al., 2013). Here, SV2C is linked to Parkinson disease.