For the CBA/Ca strain, infection with A. lumbricoides led to significant decreases in the numbers of CD8+ T cells (z ratio: −2.939, P < 0.05), αβ T cells (z ratio: −2.895, P < 0.05), NK cells (z ratio: −3.049, P < 0.05) and NKT cells (z ratio: −3.783, P < 0.01). The gene discussed is CD8A; the disease is infection.