Initially, they inherited nine DSV genes—CAB39L, GPR45, LOC1001291138, ACTR3BP5, ANP32AP1, ZBTB45, SALRNA1, XPO1, and HHIPL2—and developed cancer after acquiring five DSV genes—MGAT4A, HSPA4L, ZSCAN5A, LOC100505841, and NALCN. We focused on eight signaling pathways associated with the aforementioned DSV genes [30]. This evidence concerns the gene ZBTB45 and cancer.