Zika virus (ZIKV) replication efficiency was enhanced after METTL3 or METTL14 knockdown, modifying its host mRNA landscape [87] (Fig. 3), whereas the hepatitis C virus (HCV) infection rate was increased, not through viral RNA replication but through increased production of infectious viral particles [88] (Fig. 3). Here, METTL14 is linked to infection.