Lin S et al. revealed that METTL3 facilitated the translation of the mRNAs of epidermal growth factor receptor (EGFR) and the Hippo pathway effector TAZ to promote the progression of human lung cancer [125], which suggests that some aspects of m6A methyltransferase can regulate life processes in an m6A-independent manner. This evidence concerns the gene METTL3 and lung cancer.