TNF and herpes zoster: The IR range of OIs observed for abatacept in this analysis (0.17–0.21 per 100 patient-years, across both periods) was generally consistent with the range reported in literature for other bDMARDs; in particular, TNF inhibitors (0.15–0.30 per 100 patient-years from a US study; notably, mycobacterial infections were included but shingles (herpes zoster) was excluded from the study by Baddley et al.)[20].