As shown in Table 1, among 1412 participants in this study, those with moderate GFRcrcys (67 ≤ GFR < 80 ml/min/1.73 m2) and high GFRcrcys (≥ 80 ml/min/1.73 m2) tended to be younger; had a higher prevalence of diabetes, hypertension, higher MMSE score, and diastolic blood pressure; and had a lower prevalence of stroke, lower cystatin C, creatinine, and uric acid. The gene discussed is CST3; the disease is Hypertension.