In addition, 6-gingerol also showed a strong interaction with targets JAK2 and CASP3, while beta-sitosterol (MOL000358) and sitosterol (MOL000359) with ERBB2. These findings revealed that the six components including MOL002464, MOL002501, MOL002467, MOL000358, MOL002514, and MOL000359 were forecasted as the active components of ginger for colon cancer and TP53, HSP90AA1, and JAK2 were the major target for reaching this effect. This evidence concerns the gene TP53 and malignant colon neoplasm.