PVT1 knockdown also upregulated the expression of AJUBA (or JUB), which encodes a cell–cell junction protein [63] whose low expression is observed in metastatic prostate cancer [64], of DRAIC lncRNA, a tumor suppressor gene that represses migration and cell invasion in LNCaP cells [40], and of tumor suppressor TP53, a master regulator of stress-induced FAS-dependent apoptosis [65]. The gene discussed is TP53; the disease is metastatic prostate carcinoma.