Rong et al. observed significant correlations between a lower expression level of circPSMC3 in patients with gastric cancer and a higher TNM stage and shorter overall survival (OS) time; and circPSMC3 could participate in the progression of gastric cancer by sponging miRNA-296-5p to regulate the expression of Phosphatase and Tensin Homolog (PTEN), providing new insights into the treatment of gastric cancer [58]. Here, PTEN is linked to gastric cancer.