To investigate whether the miR-885-5p/RBBP4 axis could regulate the tumorigenesis of glioblastoma cells, we transfected si-RBBP4, miR-885-5p inhibitor or miR-885-5p inhibitor plus si-RBBP4 into U87 and U251 cells. The gene discussed is RBBP4; the disease is glioblastoma.