SLC2A4 and type 2 diabetes mellitus: For instance: (1) phloretin is a classic inhibitor of GLUT4 that has been used to block glucose transport in vitro [50]; (2) quercetin, in ob/ob T2D mice, increases Slc2a4/GLUT4 expression in muscle and improves glycemic homeostasis by decreasing the inflammatory response [112]; (3) resveratrol, in obese mice with T2D, also increases the Slc2a4/GLUT4 expression in muscle and improves glycemic control [113].