This miRNA is a direct regulator of numerous genes involved in cell proliferation and differentiation, and it shows a tumor suppressor function for several oncogenes (e.g., RAS, MYC), which may explain why a reduction in its expression in a variety of cancers has been associated with poor prognosis and increased epithelial-mesenchymal transition [43,44,45,46]. This evidence concerns the gene MYC and cancer.