Concerning the implication of HOX gene family in gliomas, previous studies have reported that the increased expression of nine genes (HOXA6, A7, A9, A13, B13, D4, D9, D10, and D13) may contribute to their malignant behavior, growth, and invasion [22], cell viability, migration, angiogenesis, stem-cell capacity, therapy resistance and decreased cell death/apoptosis in adult glioma cells [55]. The gene discussed is HOXA6; the disease is central nervous system cancer.