Furthermore, several RD1 antigens, i.e., ESAT6, CFP10, Rv3871, Rv3872 (PE35), Rv3873 (PPE68), Rv3872, Rv3876 Rv3879, and ORF14 have also been suggested for use in antibody assays for the specific diagnosis of TB [155,156,157,158,159,160,161,162,163]. This evidence concerns the gene PDE6B and tuberculosis.