Moreover, CD73 working via enzymatic generation of adenosine was important for stemness and tumor initiation capacity in high-grade serous ovarian cancer [51], confirming results of an earlier study in patients with high-grade serous ovarian cancer where tumoral expression of CD73 was associated with poor survival and was strongly correlated with an EMT gene signature [20]. Here, NT5E is linked to ovarian serous adenocarcinoma.