Furthermore, and to our surprise, the IL-1β secretion upon inflammasome induction was significantly lower in the HD patients than in the non-CKD individuals (15.39 (2.17–54.78) vs. 269.7 (29.0–1120.0) pg/mL, p = 0.020) (Figure 2a). The gene discussed is IL1B; the disease is chronic kidney disease.