Analysis of highly dilated HEVs without perivascular CCL21-detection in IDCmet− and IDCmet+ LNs showed a mix of continuous and partial expression, but never a loss of αSMA+ cells and displayed a similar pattern of αSMA distribution as non-dilated HEVs in patients with DCIS (Figure 3C). Here, ACTA1 is linked to ductal breast carcinoma in situ.