Figure 1 (row C) shows that pregnant women with ZIKV infection presented a significant increase in IL-10 and pro-inflammatory cytokines IL-6, TNF-α, IL-17A, IFN-α, and IFN-γ but not IL-1β. Although IL-2 seems to be lower in healthy pregnant women, the difference was no significant (Supplementary Table S3). Moreover, there were significant increases in serum levels of CCL2, CXCL8, CXCL9, CXCL10, IL-1RA, and IL-2R. However, unlike the changes in the remaining pro-inflammatory cytokines, the decrease in chemokines such as CCL4 and CCL11 was not significant (Supplementary Table S3). Here, CXCL8 is linked to Zika virus infectious disease.