Similarly, the estimation of molecular clock rate for datasets with the clock rate set at 0.005/36.5 subs/site/duration of infection (datasets with over 45 and up to 310 variable sites) were also highly precise and accurate, with 94% of simulations results from both models capturing true clock rate within the 95% CI and an average 95% CI width decreasing from 0.0006 to 0.0002, as more sequences were added. Here, CLOCK is linked to infection.