ITGB8 is a cell plasma membrane protein that matched with four of the nine enrichment pathways, including ‘ECM-receptor interaction,’ ‘focal adhesion,’ ‘PI3K-Art signaling pathway,’ and ‘human papillomavirus infection.’ The integrin family members play a major role in mediating the interaction between cells and the extracellular matrix (ECM) [66]. Here, ITGB8 is linked to human papilloma virus infection.