However, the Fibulin-2 protein has been described as a driver for malignant progression in lung adenocarcinomas [22,28], whereas the Fibulin 2 gene (FBLN2; chromosome 3p24-p25) has been reported to have tumour suppressive properties in nasopharyngeal carcinomas [23]. This evidence concerns the gene FBLN2 and lung adenocarcinoma.