FBLN2 and meningioma: Review of our clinical data revealed a correlation between high plasma Fibulin-2 levels and a more aggressive meningioma methylation class, (Figure 4), but did not show a correlation between Fibulin-2 levels and patient demographics, radiological findings, histological characteristics or clinical outcome, meaning that the neuro-oncological use of Fibulin-2 should be in conjunction with these other factors to predict clinical outcome.