It interacts with other ECM proteins [24] known to be widely expressed in meningiomas such as MUC4 [25], α5β1 integrins [26], laminin-α2 chain and fibronectin, to facilitate cell motility, proliferation and angiogenesis [27], but is not currently known to play any role in meningioma pathogenesis. This evidence concerns the gene MUC4 and meningioma.