That involvement was also observed in colorectal cancer cell lines using a synthetic small interfering RNA (siRNA) to attenuate the expression of SLC1A5 [29] and in non-small cell lung cancer (NSCLC) using the l-γ-glutamyl-p-nitroanilide (GPNA) ASCT2 inhibitor [80]. This evidence concerns the gene SLC1A5 and colorectal cancer.