ACHE and obesity due to melanocortin 4 receptor deficiency: Changes in in vitro health properties through inhibition of the key enzymes that control obesity (lipase), diabetes (α-glucosidase and α-amylase), hypertension (ACE), and AD (AChE, BChE, and BACE-1) of fresh tea leaves compared to the corresponding steamed and fermented tea leaves were also examined.