Unique features of MOG-AD are sensitivity to steroid use and withdrawal.[7] The patient showed good response to a small amount of steroids, consistent with the diagnosis of MOG-AD.[14] During follow-up (a minimum of 6 months), 58 (52.7%) patients with MOG-optic neuritis (MOG-ON) experienced at least one episode of recurrence of ON.[17] Age of onset may be a potential predictor for determining visual prognosis of MOG-ON.[17] Long-term outcome of patients with MOG-AD suggests infrequent relapse. This evidence concerns the gene MOG and optic neuritis.