MARCO and neoplasm: Three distinct populations in macrophages; OLR1+ macrophage population 1 (cluster 0 in Paratumor, and cluster 4 in Tumor) [22], C1QC+ macrophage population 2 (cluster 3 in Paratumor, and cluster 0, 2, 5, 6, 7 in Tumor) [24], and MARCO+ macrophage population 3 (cluster 7 in Paratumor, and cluster 8 in Tumor) [25, 26] were observed (Figure 4G).