PLK2 and Lewy body dementia: Although a substantial body of literature suggests that PLK2 is an important alpha-synuclein kinase (23, 26, 28, 30, 31, 32), potentially relevant in nonhuman primate (46) and human Lewy body disease tissue (26), genetic deletion of PLK2 in mice does not completely abolish endogenous mouse serine-129 phosphorylation (32).