<h4>Background</h4>The Met136Val mutation in SCN8A was described in a case of trigeminal neuralgia but no frequency among affected individuals was provided.<h4>Methods</h4>Direct sequencing of 123 individuals diagnosed with classic trigeminal neuralgia was performed aimed to detect the Met136Val change.<h4>Results</h4>No cases of classical trigeminal neuralgia studied had the Met136Val mutation in SCN8A.<h4>Conclusion</h4>Met136Val mutation in SCN8A is not a frequent cause of classical trigeminal neuralgia. The gene discussed is SCN8A; the disease is trigeminal nerve disorder.