We found that most host genes were overexpressed in multiple cancers besides COAD, including BRCA, LUAD, HNSC, and STAD. Other genes, including DNAH5, COL7A1, COL27A1, RP1L1, and ROBO2, seemed instead to be COAD-specific, as they were silent or even downregulated in other cancers (Figure 11A). This evidence concerns the gene RP1L1 and cancer.