PECAM1 and neoplasm: Fluorescence staining of tumor tissues by CD31/NG2 (Figure 5(A–C), p < .05) and immunohistochemical staining of tissues by VEGF-A (Figure 6(B,C-right), p < .05) revealed that ES/HA-Tyr can more effectively inhibit tumor blood vessel growth and promote tumor vessel normalization than ES.