SLC2A1 and cancer: Cancer cells are known to compensate for the lower efficiency of ATP production through glycolysis than oxidative phosphorylation by upregulating glucose transporters, such as facilitated glucose transporter member 1, GLUT1 (encoded by the SLC2A1 gene), thus increasing glucose import into the cytoplasm (Jones and Thompson, 2009; DeBerardinis et al., 2008; Hsu and Sabatini, 2008).