In T2D, expression of muscle Na+/K+ α1 and Kir6.2 increased by 24% (p = 0.045) and 36% (p = 0.029), respectively, with training, whereas no change was observed in expression of Na+/K+α2 and β1 and FXYD1 (Figure 7). The gene discussed is FXYD1; the disease is type 2 diabetes mellitus.