The higher MFN2 protein expression observed in the men with type 2 diabetes is surprising as abundance of MFN2 has been shown to correlate positively with insulin sensitivity (Bach et al., 2005) and no differences in MFN2 levels have been reported between lean and healthy as well as between obese and type 2 diabetic subjects (Gundersen et al., 2020). The gene discussed is MFN2; the disease is type 2 diabetes mellitus.