Transforming growth factor β (TGF-β) is a master regulator of an immunosuppressive action, and it is produced by both tumorigenic and immune cells and can thus orchestrate the polarization processes of the immune system toward a pro-tumorigenic phenotype and promote cancer progression and metastasis, also in TNBC (Pickup et al., 2013). Here, TGFB1 is linked to cancer.