Of importance, lower expression levels of the PDE9A, Iqca1, Sirpb1b, CD244, SP140, and PIP5k1b genes was found in the BC patients with unfavorable prognosis in terms of 5-year survival analysis (dataset of Breast Invasive Carcinoma [n = 1075] from TCGA) (Figure S11). The gene discussed is PDE9A; the disease is invasive breast carcinoma.