In this way, a platelet RNA sequencing study of 25 COVID-19 patients demonstrated that platelets do not express the ACE2 receptor, although mRNA from the SARS-CoV-2 N1 gene was detected in platelets from 2/25 COVID-19 patients, suggesting that platelets may take-up SARS-CoV-2 mRNA independent of ACE2. Here, ACE2 is linked to COVID-19.