Cytokines/chemokines IL-1β, IL-6, IL-7, IL-8, IL-9, IL-10, CXCL10, CCL2, CCL3, CCL4, TNF-α, IL-12, and IL-17, have been described in high levels on plasma/serum samples from patients with severe COVID-19 and even higher in patients prior to death [40]. The gene discussed is TNF; the disease is COVID-19.