Kawasaki et al. compared the serum cytokine levels of IMN children with lupus nephritis children, MPGN, Henoch-Schönlein purpura nephritis, and IgA nephritis, and found that serum IL-2, IL-6, IL-12, and IFN-γ were not significantly increased, while the contents of IL-4 were significantly increased [109]. The gene discussed is IL4; the disease is primary membranoproliferative glomerulonephritis.