CD4 and gastric cancer: The parabolic type of immune cells included activated B cell, activated CD4 T cell, activated CD8 T cell, effector memory CD8 T cell, MDSC, memory B cell, regulatory T cell, type 1 T helper cell, and type 2 T helper cells, which were common from normal gastric mucosa to superficial, atrophic, and extensive atrophic gastritis till T1/T2 stage gastric cancer (Figure 3(a)).