AKT1 and cholangiocarcinoma: The profiles showed that different hub targets are differentially expressed in multiple tumor tissues (Figure 13), and AKT1, TP53, VEGFA, and EGFR are differentially expressed between multiple tumors and adjacent normal tissues (Figure 14), such as breast invasive carcinoma, cholangiocarcinoma, prostate adenocarcinoma, and thyroid carcinoma.