Similar peptide-based panning strategy has been used to isolate VHH against breast carcinoma proteins–Muc-1 (Rahbarizadeh et al., 2004), CD44 (Kavousipour et al., 2018), and ScFv against human angiotensin-I (Cobaugh et al., 2008) and CXC chemokine receptor-2 (Boshuizen et al., 2014). The gene discussed is CXCR2; the disease is breast carcinoma.