Recovery of liver function and improved liver fibrosis with prolonged presence of transplanted BM-MSCs in the liver: reduction in the expression of pro-inflammatory cytokines (IL-1β, IL-6, and IFN-γ) and of pro-fibrogenic factors (TGF-β1, α-SMA, and CTGF) and increase in the expression of anti-fibrogenic factors (CK-18 and HGF). The gene discussed is CCN2; the disease is Hepatic fibrosis.