We detected increased protein levels of p-Erk/Erk, p-AKT/AKT, p-p38/p38, p-TAK1/TAK1, and p-NF-κB/NF-κB in IL-1β-treated OA-CH compared to controls (absence of IL-1β). This evidence concerns the gene AKT1 and cyclic hematopoiesis.