CACNA1A and episodic ataxia type 2: Traditionally, heterozygous pathogenic variants in CACNA1A may lead to several different phenotypes, including familial/sporadic hemiplegic migraine type 1 (FHM1/SHM1, MIM#141500), familial hemiplegic migraine with progressive cerebellar ataxia (MIM#141500), episodic ataxia type 2 (EA2, MIM#108500), and spinocerebellar ataxia type 6 (SCA6, MIM#183086).