IL10 and coccidioidomycosis: However, it is important to mention that in a mouse model of coccidioidomycosis, it was observed that lung-infiltrated neutrophils produce high amounts of IL-10, a fact that was associated with impairment of resistance to coccidioidal infection due to a suppression of Th1, Th2, and Th17 immunity mediated by this anti-inflammatory cytokine (Hung et al., 2013).