CLEC7A and infection: Regarding CTL receptors, it has been reported that Dectin-1 has a critical influence in the differentiation and migration of Tc17 cells; thus, Dectin-1 deficient mice infected with P. brasiliensis showed a more severe infection, enhanced tissue pathology, and mortality rates, accompanied with reduced differentiation of T cells to Tc17 phenotype, increased expansion of Treg cells, impaired production of Th1, Th2, and Th17 cytokines, and migration of Tc17 and neutrophils to the site of infection (Loures et al., 2014).