Moreover, an additional study showed that IFN-γ−/− knock-out mice immunized with the ΔT vaccine could still be protected (100% survival), while only 40% of ΔT-vaccinated IL17 receptor A-deficient mice survived (Hung et al., 2011); again, this study shows that Th17/IL-17 axis contributes strongly to protection against Coccidioides infection. This evidence concerns the gene IL17A and coccidioidomycosis.