HTRA3 and neoplasm: The expression of HTRA3 was negatively correlated with the abundance of acquired immunocytes [helper T17 (Th17) cells, T helper cells, T central memory cells, etc.], and positively correlated with the abundance of innate immunocytes [natural killer (NK) cells, tumor-associated macrophages (TAMs), immature dendritic cells, etc.] (Figures 3A–G, P < 0.001).