To verify whether miR-608 can inhibit the proliferation of RCC by inhibiting TFE3, we transfected 786-O and Caki-1 cells with Control+miR-NC, Control+miR-608 mimic, TFE3+miR-NC, or TFE3+miR-608 mimics. This evidence concerns the gene TFE3 and renal cell carcinoma.