SHOX2 and lung cancer: As shown in Figure 2, the significantly higher SHOX2 (A, 4.9 ± 2.7) and RASSF1A (B: 6.5 ± 3.6) DNA methylation (lower ΔCts) can be found in FFPE samples from lung cancer cases in comparison to the benign lesion controls (A, 9.4 ± 0.8; B, 12.9 ± 2.1).