PTH and posterior cortical atrophy: Other bone-related markers frequently measured are 1) parathyroid hormone (PTH), a marker of osteoblastic activity and a major determinant of bone resorption and of PCa cell proliferation and migration, whose levels can be decreased by bone-targeted therapies (BTT) and by vitamin D (vitD) supplementation; 2) vitD, frequently deficient in elderly males, that enhances bone resorption to increase calcium bioavailability [18], [19], [20], [21], [22], [23].